Patricia E Carreira, Adam D Ewing, Guibo Li, Stephanie N Schauer, Kyle R Upton, Allister C Fagg, Santiago Morell, Michaela Kindlova, Patricia Gerdes, Sandra R Richardson, Bo Li, Daniel J Gerhardt, Jun Wang, Paul M Brennan, Geoffrey J Faulkner: Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme. In: Mob. DNA, 7 (1), pp. 21, 2016.

Abstract

LINE-1 (L1) retrotransposons are a notable endogenous source of
mutagenesis in mammals. Notably, cancer cells can support unusual
L1 retrotransposition and L1-associated sequence rearrangement
mechanisms following DNA damage. Recent reports suggest that L1
is mobile in epithelial tumours and neural cells but,
paradoxically, not in brain cancers.

BibTeX (Download)

@article{Carreira2016-vr,
title = {Evidence for L1-associated DNA rearrangements and negligible  L1 retrotransposition in glioblastoma multiforme},
author = {Patricia E Carreira and Adam D Ewing and Guibo Li and Stephanie N Schauer and Kyle R Upton and Allister C Fagg and Santiago Morell and Michaela Kindlova and Patricia Gerdes and Sandra R Richardson and Bo Li and Daniel J Gerhardt and Jun Wang and Paul M Brennan and Geoffrey J Faulkner},
url = {http://dx.doi.org/10.1186/s13100-016-0076-6},
year  = {2016},
date = {2016-01-01},
journal = {Mob. DNA},
volume = {7},
number = {1},
pages = {21},
abstract = {LINE-1 (L1) retrotransposons are a notable endogenous source of 
 mutagenesis in mammals. Notably, cancer cells can support unusual 
 L1 retrotransposition and L1-associated sequence rearrangement 
 mechanisms following DNA damage. Recent reports suggest that L1 
 is mobile in epithelial tumours and neural cells but, 
 paradoxically, not in brain cancers.},
keywords = {Faulknerlab},
pubstate = {published},
tppubtype = {article}
}