Samuel Jesuadian obtained his Bachelor degree in Plant biology and Biotechnology from Bharathidasan University, India in 2006, where he was awarded the university top rank holder. Upon completion of his bachelor’s degree, he moved to Australia to pursue Master’s Degree in Biotechnology at Griffith University, QLD. As part of his Master’s degree, he successfully completed a one year dissertation programme at DPI in UQ, St.Lucia, QLD which involved research activities in Bovine respiratory disease. In 2008 he was graduated from Master’s degree with class I honours.From 2008 to 2010, he was working as a research assistant at National Adult Stem Cell Centre within Eskitis Institute, Griffith University, QLD. During this period he was involved with research projects that develop therapies for regeneration of the brain using glial cells and developing molecular profile of the proliferative dye labelled (EDU) cells in the mouse olfactory epithelium.
In 2010, Samuel Jesuadian started working as a senior research technician at UQCCR, Herston within Fetal Medicine Research Group. This position provided him to widen his career platform into clinical research. He was actively involved in pre-clinical projects such as; intrauterine transplantation of fetal mesenchymal stem cells for osteogenesis imperfecta and discordant placental mRNA expression in complicated monochorionic twins. He was also enhanced his skills on research ethics management and animal colony management during this term.
Samuel Jesuadian has been in his current position with Genome Plasticity and Disease group since January 2013. Since he started this position, he has been working on mapping LINE-1 mutation in human brain on a single cell level. This has been published recently, Upton et al, (Cell, 2015) and this is his first achievement on publishing as a co-first author. He also manages the operational management of the team and provides support on Animal ethics; OGTR and IBC regulatory requirements for the team.
LINE-1 Evasion of Epigenetic Repression in Humans (Journal Article)
Molecular Cell, 0 (0), 2019, ISSN: 1097-2765.
L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution (Journal Article)
Cell Reports, 23 (13), pp. 3730–3740, 2018, ISSN: 2211-1247.
Genome Res., 27 (8), pp. 1395–1405, 2017.
Ubiquitous L1 mosaicism in hippocampal neurons (Journal Article)
Cell, 161 (2), pp. 228–239, 2015.
Ryan JM, Matigian N, Pelekanos RA, Jesuadian S, Wells CA., Fisk NM. Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: Gestational age versus niche. Elsevier (2014)